Korean Journal of Nephrology 2008;27(2):251-255.
A Case of End-Stage Renal Disease (ESRD) from Reflux Nephropathy in a patient with Situs Inversus and Duplicated Ureter
Young Keun Kim, M.D.1, Min-Ok Kim, M.D.1 , So Yeon Choi, M.D.1, Hyun-Ju Choi, M.D.1, Hyun Young Han, M.D.2, Woo Seong Huh3, Ha Young Oh3 and Sung-Joo Kim4
Department of Internal Medicine1
Department of Radiology2
Eulji University Hospital, Daejeon, Korea; Department of Internal Medicine3
Department of Surgery4
Samsung Medical Center; Sungkyunkwan University, Seoul, Korea
증례 : 내장 역위증과 중복요관이 동반된 환자에서 발생한 방광요관역류로 인한 말기신부전 1예
김영근1, 김민옥1, 최소연1, 최현주1, 한현영2, 허우성3, 오하영3, 김성주4
을지대학교 을지대학병원 내과학교실1, 영상의학교실2, 성균관대학교 내과학교실3, 성균관대학교 외과학교실4
Abstract
Situs inversus is a rare congenital anomaly that occurs in adults at the rate of 1:5,000-1:10,000. In the total form, the thoracic organs, as well as the abdominal organs, are completely reversed in a "mirror image" of their normal arrangements. Ureteral duplication is the most common ureteral anomaly founded incidentally. However, there is a higher incidence of duplication in cases of urinary tract infection, and it may be associated with upper urinary tract stasis, obstruction, or reflux. But ureteral duplication has no relation to situs inversus. Vesicoureteral reflux (VUR) is the most common disorder usually detected during radiologic evaluation of children with urinary tract infection. Complications such as renal scarring, reflux nephropathy, chronic renal failure and hypertension are well known in patients with VUR. Reflux nephropathy is responsible for about 10% of all cases of treated ESRD and is the most common case of ESRD in children. Thus, if VUR exists, early diagnosis and intensive treatment is necessary. Herein, we present a case of reflux nephropathy related ESRD in a 41-year-old woman with total situs inversus and duplicated ureter.
Key Words: Situs inversus, Vesico-ureteral reflux, End stage renal disease (ESRD)
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